Design, synthesis and biological evaluation of pleiotropic prodrugs activated by cholinesterases and releasing a 5-HT4R agonist, with in vivo antiamnesic activity.

Alice Wang, Caroline Lahogue, Thomas Curel, Caroline Lanthier, Anne-Claire Groo, Audrey Davis, Sophie Corvaisier, Dimitri Fayolle, Fabrice Modeste, Xavier Brazzolotto, Florian Nachon, Cédric Lecoutey, Sylvie Claeysen, Aurélie Malzert-Fréon, Thomas Freret, Michel Boulouard, Marc Since, Christophe Rochais, Patrick Dallemagne

DOI: 10.1016/j.ejmech.2026.119383

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